MAXYGEN, INC.

A REVOLUTION IN EVOLUTION

DIRECTED EVOLUTION SERVICES, NAMELY, THE RECOMBINATION OF GENES CUSTOMIZED TO THE SPECIFICATION OF OTHERS TO PRODUCE NOVEL GENE SEQUENCES FOR USE IN SCIENCE, RESEARCH, CHEMISTRY, AGRICULTURE, MEDICINE AND INDUSTRY;PHARMACEUTICAL PREPARATIONS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, DENTAL AND PERIODONTAL, DERMATOLOGIC, ENDOCRINE AND METABOLIC, GASTROINTESTINAL,GENETIC, HEMATOLOGIC, HEPATIC, IMMUNOLOGIC, LYMPHATIC, OSTEOLOGIC, NEUROLOGIC, OPHTHALMIC, PSYCHIATRIC, RESPIRATORY TRACT, AND RENAL AND URINARY TRACT DISEASES AND DISORDERS; PHARMACEUTICAL PREPARATIONS, NAMELY, ANALGESICS, ANTIBIOTICS, ANTI-CANCER PREPARATIONS, ANTI-INFECTIVES, ANTI-PARASITICS, ANTIVIRALS, VACCINES, INSULIN AND ADJUVANTS FOR USE WITH THE AFORESAID PREPARATIONS; MEDICAL DIAGNOSTIC PREPARATIONS AND REAGENTS; HERBICIDES, PESTICIDES, BIOPESTICIDES, MITICIDES, AND WEED KILLERS, ALL FOR AGRICULTURAL AND DOMESTIC USE; HORMONES;BIOCHEMICALS, NAMELY POLYNUCLEIC ACIDS AND POLYPEPTIDES FOR SCIENTIFIC, RESEARCH AND COMMERCIAL USE; BIOCHEMICALS FOR IN VITRO AND IN VIVO SCIENTIFIC, RESEARCH AND COMMERCIAL USE; PLANT GROWTH REGULATORS, POLYPEPTIDES, GENES, AND POLYNUCLEIC ACIDS FOR AGRICULTURAL USE; AND GENES AND ENZYMES USED TO PRODUCE CHEMICALS FOR RESEARCH AND COMMERCIAL APPLICATIONS PERTAINING TO CHEMISTRY, BIOCHEMISTRY, BIOLOGY, AGRICULTURE PHARMACEUTICALS, DIAGNOSTICS, MEDICINE, BIOREMEDIATION, DECONTAMINATION, DETOXIFICATION, AND CLEANING;LIVING PLANTS, NAMELY TRANSGENIC PLANTS;CHEMICAL RESEARCH SERVICES; SCIENTIFIC RESEARCH SERVICES; RESEARCH AND TESTING SERVICES IN THE FIELDS OF BACTERIOLOGY AND VIROLOGY; RESEARCH AND PRODUCT DEVELOPMENT SERVICES IN THE FIELDS OF GENETICS AND GENE THERAPY, TRANSGENIC PLANTS, CHEMISTRY, PHARMACEUTICALS, MEDICAL DIAGNOSTICS, HERBICIDES, PESTICIDES, BIOPESTICIDES, CYTOTOXIC AGENTS, BACTERIOLOGY, VIROLOGY, BIOCATALYSIS, METABOLIC PATHWAYS, AND BIOCHEMICAL PATHWAYS;

DNASHUFFLING

DIRECTED EVOLUTION SERVICES, NAMELY, THE RECOMBINATION OF GENES CUSTOMIZED TO THE SPECIFICATION OF OTHERS TO PRODUCE NOVEL GENE SEQUENCES FOR USE IN SCIENCE, RESEARCH, CHEMISTRY, AGRICULTURE, MEDICINE AND INDUSTRY;DNA SHUFFLING;CHEMICAL RESEARCH SERVICES; SCIENTIFIC RESEARCH SERVICES; RESEARCH AND TESTING SERVICES IN THE FIELDS OF BACTERIOLOGY AND VIROLOGY; RESEARCH AND PRODUCT DEVELOPMENT SERVICES OF OTHERS IN THE FIELDS OF GENETICS AND GENE THERAPY, TRANSGENIC PLANTS, CHEMISTRY, PHARMACEUTICALS, MEDICAL DIAGNOSTICS, HERBICIDES, PESTICIDES, BIOPESTICIDES, CYTOTOXIC AGENTS, BACTERIOLOGY, VIROLOGY, BIOCATALYSIS, METABOLIC PATHWAYS, AND BIOCHEMICAL PATHWAYS, AND OTHER UTILITIES;

FAMILYSHUFFLING

DIRECTED EVOLUTION SERVICES, NAMELY THE RECOMBINATION OF GENES FOR THE BENEFIT OF OTHERS TO PRODUCE NOVEL GENE SEQUENCES FOR USE IN SCIENCE, RESEARCH, CHEMISTRY, AGRICULTURE, MEDICINES AND INDUSTRY;FAMILY SHUFFLING;

GENEHARVEST

directed evolution services, namely the recombination of genes for the benefit of others to produce novel genes and proteins for use in science, research, chemistry, agriculture, pharmaceuticals, diagnostics, vaccines, medicine and industry; manufacture of chemicals for others;pharmaceutical preparations for the prevention and treatment of cardiovascular, dental and periodontal, dermatologic, endocrine and metabolic, gastrointestinal, genetic, hematologic, hepatic, immunologic, lymphatic, osteologic, neurologic, ophthalmic, psychiatric, respiratory tract, and renal and urinary tract diseases and disorders; pharmaceutical preparations, namely, analgesics, antibiotics, anti-cancer preparations; anti-infectives, anti-parasitics, antivirals; insulin; hormones; medical diagnostic preparations and reagents; herbicides, pesticides, biopesticides, miticides, and weedkillers, all for agricultural and domestic use; vaccines; adjuvants for use with vaccines;GENE HARVEST;chemicals and biochemicals, namely, genes and proteins, prokaryotic and eukaryotic strains, and chemical and biochemical catalysts, namely all used for scientific, research and commercial applications pertaining to chemistry, biochemistry, biology, agriculture, nutrition, chemicals, pharmaceuticals, diagnostics, medicine, bioremediation, decontamination, detoxification, and cleaning;chemical research services; scientific research services; research, product development, and process development services for others in the fields of genetics, gene therapy, vaccines, transgenic plants, chemistry, pharmaceuticals, diagnostics, herbicides, pesticides, biopesticides, cytotoxic agents, bacteriology, biocatalysis, metabolic pathways and biochemical pathways;

GENESHUFFLING

directed evolution services, namely the recombination of genes customized to the specification of others to produce novel gene sequences for use in science, research, chemistry, agriculture, medicine, and industry;GENE SHUFFLING;chemical research services; scientific research services; research and testing services in the fields of bacteriology and virology; research and product development services for others in the fields of genetics and gene therapy, transgenic plants, chemistry, pharmaceuticals, medical diagnostics, herbicides, pesticides, biopesticides, cytotoxic agents, bacteriology, virology, biocatalysis, metabolic pathways, and biochemical pathways, and other utilities;

MAXIMIZING GENETIC DIVERSITY

DIRECTED EVOLUTION SERVICES, NAMELY, THE RECOMBINATION OF GENES CUSTOMIZED TO THE SPECIFICATION OF OTHERS TO PRODUCE NOVEL GENE SEQUENCES FOR USE IN SCIENCE, RESEARCH, CHEMISTRY, AGRICULTURE, MEDICINE AND INDUSTRY;PHARMACEUTICAL PREPARATIONS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, DENTAL AND PERIODONTAL, DERMATOLOGIC, ENDOCRINE AND METABOLIC, GASTROINTESTINAL,GENETIC, HEMATOLOGIC, HEPATIC, IMMUNOLOGIC, LYMPHATIC, OSTEOLOGIC, NEUROLOGIC, OPHTHALMIC, PSYCHIATRIC, RESPIRATORY TRACT, AND RENAL AND URINARY TRACT DISEASES AND DISORDERS; PHARMACEUTICAL PREPARATIONS, NAMELY, ANALGESICS, ANTIBIOTICS, ANTI-CANCER PREPARATIONS, ANTI-INFECTIVES, ANTI-PARASITICS, ANTIVIRALS, VACCINES, INSULIN AND ADJUVANTS FOR USE WITH THE AFORESAID PREPARATIONS; MEDICAL DIAGNOSTIC PREPARATIONS AND REAGENTS; HERBICIDES, PESTICIDES, BIOPESTICIDES, MITICIDES, AND WEED KILLERS, ALL FOR AGRICULTURAL AND DOMESTIC USE; HORMONES;BIOCHEMICALS, NAMELY POLYNUCLEIC ACIDS AND POLYPEPTIDES FOR SCIENTIFIC, RESEARCH AND COMMERCIAL USE; BIOCHEMICALS FOR IN VITRO AND IN VIVO SCIENTIFIC, RESEARCH AND COMMERCIAL USE; PLANT GROWTH REGULATORS, POLYPEPTIDES, GENES, AND POLYNUCLEIC ACIDS FOR AGRICULTURAL USE; AND GENES AND ENZYMES USED TO PRODUCE CHEMICALS FOR RESEARCH AND COMMERCIAL APPLICATIONS PERTAINING TO CHEMISTRY, BIOCHEMISTRY, BIOLOGY, AGRICULTURE, PHARMACEUTICALS, DIAGNOSTICS, MEDICINE, BIOREMEDIATION, DECONTAMINATION, DETOXIFICATION, AND CLEANING;LIVING PLANTS, NAMELY TRANSGENIC PLANTS;CHEMICAL RESEARCH SERVICES; SCIENTIFIC RESEARCH SERVICES; RESEARCH AND TESTING SERVICES IN THE FIELDS OF BACTERIOLOGY AND VIROLOGY; RESEARCH AND PRODUCT DEVELOPMENT SERVICES IN THE FIELDS OF GENETICS AND GENE THERAPY, TRANSGENIC PLANTS, CHEMISTRY, PHARMACEUTICALS, MEDICAL DIAGNOSTICS, HERBICIDES, PESTICIDES, BIOPESTICIDES, CYTOTOXIC AGENTS, BACTERIOLOGY, VIROLOGY, BIOCATALYSIS, METABOLIC PATHWAYS, AND BIOCHEMICAL PATHWAYS;

MAXYAG

MAXI YAG;BIOCHEMICALS, NAMELY POLYPEPTIDES FOR SCIENTIFIC AND RESEARCH USE; BIOCHEMICALS FOR IN VITRO SCIENTIFIC AND RESEARCH USE; POLYPEPTIDES FOR AGRICULTURAL USE;

MAXYCHEM

DIRECTED EVOLUTION SERVICES, NAMELY THE RECOMBINATION OF GENES FOR THE BENEFIT OF OTHERS TO PRODUCE NOVEL GENE SEQUENCES FOR USE IN SCIENCE, RESEARCH, CHEMISTRY, AGRICULTURE, MEDICINES AND INDUSTRY;BIOCHEMICALS, NAMELY POLYNUCLEIC ACIDS AND POLYPEPTIDES FOR SCIENTIFIC, RESEARCH AND COMMERCIAL USE; BIOCHEMICALS FOR IN VITRO AND IN VIVO SCIENTIFIC, RESEARCH AND COMMERCIAL USE; PLANT GROWTH REGULATORS, POLYPEPTIDES, GENES, AND POLYNUCLEIC ACIDS FOR AGRICULTURAL USE; AND GENES AND ENZYMES USED TO PRODUCE CHEMICALS FOR RESEARCH AND COMMERCIAL APPLICATIONS PERTAINING TO CHEMISTRY, BIOCHEMISTRY, BIOLOGY, AGRICULTURE PHARMACEUTICALS, DIAGNOSTICS, MEDICINE, BIOREMEDIATION, DECONTAMINATION, DETOXIFICATION, AND CLEANING;CHEMICAL RESEARCH SERVICES; SCIENTIFIC RESEARCH SERVICES; RESEARCH AND TESTING SERVICES IN THE FIELDS OF BACTERIOLOGY AND VIROLOGY; RESEARCH AND PRODUCT DEVELOPMENT SERVICES FOR OTHERS IN THE FIELDS OF GENETICS AND GENE THERAPY, TRANSGENIC PLANTS, CHEMISTRY, PHARMACEUTICALS, MEDICAL DIAGNOSTICS, HERBICIDES, PESTICIDES, BIOPESTICIDES CYTOTOXIC AGENTS, BACTERIOLOGY, VIROLOGY, BIOCATALYSIS, METABOLIC PATHWAYS AND BIOCHEMICAL PATHWAYS, AND OTHER UTILITIES;

MAXYGEN

scientific research; bacteriological and virological research; laboratory research in the field of genetics pharmaceuticals, bacteriology, virology, and research and product development services for others in the fields of genetics pharmaceuticals, bacteriology, virology;

MAXYGEN

directed evolution services, namely the recombination of genes customized to the specification of others to produce novel gene sequences for use in science, research, chemistry, agriculture, medicine, and industry;scientific research services; research in the fields of bacteriology and virology; research and product development services for others in the fields of genetics pharmaceuticals, bacteriology, and virology;

MAXYGEN

Pharmaceutical preparations for the prevention and treatment of cardiovascular, dental and periodontal, dermatologic, endocrine and metabolic, gastrointestinal, genetic, hematologic, hepatic, immunologic, lymphatic, osteologic, neurologic, ophthalmic, psychiatric, respiratory tract, and renal and urinary tract diseases and disorders; pharamaceutical preparations, namely, analgesics, antibotics, anti-cancer preparations, anti-infectives, anti-parasitics, antivirals; insulin; hormones; medical diagnostic preparations and reagents; vaccines; adjuvants for use with vaccines;Biochemicals, namely, polynucleic acids and polypeptides for commercial use; biochemicals for in vitro and in vivo commercial use; genes for commercial applications pertaining to chemistry, biochemistry, biology, pharmaceuticals, diagnostics and medicine; genes for research applications pertaining to chemistry and diagnostics; enzymes used to produce chemicals for research and commercial applications pertaining to chemistry, biochemistry, biology, pharmaceuticals, diagnostics and medicine;Chemical research services; testing services in the fields of bacteriology and virology; research and product development services for others in the fields gene therapy, chemistry, medical diagnostics; cytotoxic agents, metabolic pathways, , and other utilities;

MAXYGEN

Directed evolution services, namely, the recombination of genes customized to the specification of others to produce novel gene sequences for use in science, research, medicine, [ and industry ];Scientific research services; research in the fields of bacteriology and virology; research and product development services for others in the fields of genetics, pharmaceuticals, bacteriology, and virology;

MAXYGEN

Biochemicals, namely, polynucleic acids [ and polypeptides for ] scientific and research use; biochemicals for in vivo and in vitro scientific and research use [ ; and genes for research applications pertaining to biochemistry, biology, pharmaceuticals and medicine ];

MAXYGENE

directed evolution services, namely the recombination of genes customized to the specification of others to produce novel gene sequences for use in science, research, chemistry, agriculture, medicine, and industry;pharmaceutical preparations for the prevention and treatment of cardiovascular, dental and periodontal, dermatologic, endocrine and metabolic, gastrointestinal, genetic, hematologic, hepatic, immunologic, lymphatic, osteologic, neurologic, ophthalmic, psychiatric, respiratory tract, and renal and urinary tract diseases and disorders; pharmaceutical preparations, namely, analgesics, antibiotics, anti-cancer preparations, anti-infectives, anti-parsitics, antivirals; insulin; hormones; medical diagnostic preparations and reagents; herbicides, pesticides, biopesticides, miticides, and weed killers, all for agricultural and domestic use; vaccines; adjuvents for use with vaccines;MAXY GENE;biochemicals, namely, polynucleic acids and polypeptides for scientific, research and commercial use; biochemicals for in vitro and in vivo scientific, research and commercial use; plant growth regulators; polypeptides, genes and polynucleic acids for agricultural use; and genes and enzymes used to produce chemicals for research and commercial applications pertaining to chemistry, biochemistry, biology, agriculture, pharmaceuticals, diagnostics, medicine, bioremediation, decontamination, detoxification, and cleaning;living plants, namely transgenic plants;chemical research services; scientific research services; research and testing services in the fields of bacteriology and virology; research and product development services for others in the fields of genetics and gene therapy, transgenic plants, chemistry, pharmaceuticals, medical diagnostics, pesticides, biopesticides, cytotoxic agents, bacteriology, virology, biocatalysis, metabolic pathways and biochemical pathways;

MAXYGENE INSIDE

directed evolution services, namely, the recombination of genes customized to the specification of others to produce novel gene sequences for use in science, research, chemistry, agriculture, medicine, and industry;pharmaceutical preparations for the prevention and treatment of cardiovascular, dental and periodontal, dermatologic, endocrine and metabolic, gastrointestinal, genetic, hematologic, hepatic, immunologic, lymphatic, osteologic, neurologic, ophthalmic, psychiatric, respiratory tract, and renal and urinary tract diseases and disorders; pharmaceutical preparations, namely, analgesics, antibiotics, anti-cancer preparations, anti-infectives, anti-parasitic, antivirals; insulin; hormones; medical diagnostic preparations and reagents; herbicides, pesticides, biopesticides, miticides, and weed killers, all for agricultural and domestic use; vaccines; adjuvants for use with vaccines;MAXY GENE INSIDE;biochemicals, namely, polynucleic acids and polypeptides for scientific, research and commercial use; biochemicals for in vitro and in vivo scientific, research and commercial use; plant growth regulators; polypeptides, genes and polynucleic acids for agricultural use; and genes and enzymes used to produce chemicals for research and commercial applications pertaining to chemistry, biochemistry, biology, agriculture, pharmaceuticals, diagnostics, medicine, bioremediation, decontamination, detoxification, and cleaning;living plants, namely, transgenic plants;chemical research services; scientific research services; research and testing services in the fields of bacteriology and virology; research and product development services for others in the fields of genetics and gene therapy, transgenic plants, chemistry, pharmaceuticals, medical diagnostics, pesticides, biopesticides, cytotoxic agents, bacteriology, virology, biocatalysis, metabolic pathways and biochemical pathways;

MAXYPRO

PHARMACEUTICAL PREPARATIONS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR, DENTAL AND PERIODONTAL, DERMATOLOGIC, ENDOCRINE AND METABOLIC, GASTROINTESTINAL, GENETIC, HEMATOLOGIC, HEPATIC, IMMUNOLOGIC, LYMPHATIC, OSTEOLOGIC, NEUROLOGIC, OPHTHALMIC, PSYCHIATRIC, RESPIRATORY TRACT, AND RENAL AND URINARY TRACT DISEASES AND DISORDERS; PHARMACEUTICAL PREPARATIONS, NAMELY, ANALGESICS, ANTIBIOTICS, ANTI-CANCER PREPARATIONS, ANTI-INFECTIVES, ANTI-PARASITICS, ANTIVIRALS, VACCINES AND ADJUVANTS FOR USE WITH THE AFORESAID PHARMACEUTICAL PREPARATIONS; INSULIN; HORMONES;MAX PRO;

NEWHARVEST

directed evolution services, namely the recombination of genes for the benefit of others to produce novel genes and proteins for use in science, research, chemistry, agriculture, pharmaceuticals, diagnostics, vaccines, medicine and industry; manufacture of chemicals for others;pharmaceutical preparations for prevention and treatment of cardiovascular, dental and periodontal, dermatologic, endocrine and metabolic, gastrointestinal, genetic, hematologic, hepatic, immunologic, lymphatic, osteologic, neurologic, ophthalmic, psychiatric, respiratory tract, and renal and urinary tract diseases and disorders; pharmaceutical preparations, namely, analgesics, antibiotics, anti-cancer preparations; anti-infectives, anti-parasitics, antivirals; insulin; hormones; medical diagnostic preparation and reagents; herbicides, pesticides, biopesticides, miticides, and weedkillers, all for agricultural and domestic use; vaccines; adjuvants for use with vaccines;NEW HARVEST;chemicals and biochemicals, namely, genes and proteins, prokaryotic and eukaryotic strains, and chemical and biochemical catalysts, all used for scientific, research and commercial applications pertaining to chemistry, biochemistry, biology, agriculture, nutrition, chemicals, pharmaceuticals, diagnostics, medicine, bioremediation, decontamination, detoxification, and cleaning;chemical research services; scientific research services; research, product development, and process development services for others in the fields of genetics, gene therapy, vaccines, transgenic plants, chemistry, pharmaceuticals, diagnostics, herbicides, pesticides, biopesticides, cytotoxic agents, bacteriology, biocatalysis, metabolic pathways and biochemical pathways;

SPREEDBREEDING

DIRECTED EVOLUTION SERVICES, NAMELY THE RECOMBINATION OF GENES FOR THE BENEFIT OF OTHERS TO PRODUCE NOVEL GENE SEQUENCES FOR USE IN SCIENCE, RESEARCH, CHEMISTRY, AGRICULTURE, MEDICINES AND INDUSTRY;SPEED BREEDING;CHEMICAL RESEARCH SERVICES; SCIENTIFIC RESEARCH SERVICES; RESEARCH AND TESTING SERVICES IN THE FIELDS OF BACTERIOLOGY AND VIROLOGY; RESEARCH AND PRODUCT DEVELOPMENT SERVICES FOR OTHERS IN THE FIELDS OF GENETICS AND GENE THERAPY, TRANSGENIC PLANTS, CHEMISTRY, PHARMACEUTICALS, MEDICAL DIAGNOSTICS, HERBICIDES, PESTICIDES, BIOPESTICIDES, CYTOTOXIC AGENTS, BACTERIOLOGY, VIROLOGY, BIOCATALYSIS, METABOLIC PATHWAYS, AND BIOCHEMICAL PATHWAYS, AND OTHER UTILITIES;