SYNTHETIC LIGANDS TARGETING PROTEINS

Brand Owner (click to sort) Address Description
MIMETIC BLUE ASTREA UK SERVICES LIMITED Unit 1 Horizon Park, Barton Road Comberton, Cambridge CB237AJ United Kingdom synthetic ligands for targeting proteins for biotechnology research, biopharmaceutical research and medical research laboratories;MIMETIC;
MIMETIC BLUE ASTREA BIOSEPARATIONS LTD FREEPORT, BALLASALLA ISLE OF MAN, BRITISH ISLES IM9 2AP synthetic ligands for targeting proteins for biotechnology research, biopharmaceutical research and medical research laboratories;MIMETIC;
MIMETIC GREEN PROMETIC BIOSCIENCES, LTD. FREEPORT, BALLASALLA ISLE OF MAN, BRITISH ISLES 1MP 2AP United Kingdom synthetic ligands for targeting proteins for biotechnology research, biopharmaceutical research and medical research laboratories;MIMETIC;
MIMETIC ORANGE PROMETIC BIOSCIENCES, LTD. FREEPORT, BALLASALLA ISLE OF MAN, BRITISH ISLES 1MP 2AP United Kingdom synthetic ligands for targeting proteins for biotechnology research, biopharmaceutical research and medical research laboratories;MIMETIC;
MIMETIC RED PROMETIC BIOSCIENCES, LTD. FREEPORT, BALLASALLA ISLE OF MAN, BRITISH ISLES 1MP 2AP United Kingdom synthetic ligands for targeting proteins for biotechnology research, biopharmaceutical research and medical research laboratories;MIMETIC;
MIMETIC YELLOW PROMETIC BIOSCIENCES, LTD. FREEPORT, BALLASALLA ISLE OF MAN, BRITISH ISLES 1MP 2AP United Kingdom synthetic ligands for targeting proteins for biotechnology research, biopharmaceutical research and medical research laboratories;MIMETIC;
 

Where the owner name is not linked, that owner no longer owns the brand

    
Technical Examples
  1. The present invention is based on the discovery that proteins produced in insect cell cultures are glycosylated in a unique manner that causes them to be selectively imported by cells that express mannose receptors on their membranes, particularly macrophages. Proteins that are selectively imported into cells containing mannose receptors are provided, as well as pharmaceutical compositions containing such proteins and methods for producing such proteins. Application of the present invention to produce proteins useful for treating lysosomal storage disorders is also disclosed. Engineering of cells to express mannose receptors so that they will selectively import proteins produced in insect cells is also taught, as well as a protein targeting system using such cells and proteins. Finally, an improved elution buffer for the purification of proteins produced in insect cells from a Concanavalin A column is provided.