RIBOZYMES WHICH ACT AS POLYMERASES

Brand	Owner	Address	Description
RNAZYME	AMERSHAM INTERNATIONAL PLC	AMERSHAM PLACE LITTLE CHALFONT, BUCHINGHAMSHIRE	RIBOZYMES WHICH ACT AS POLYMERASES, DEPHOSPHORYLASES, OR SEQUENCE-SPECIFIC ENDORIBONUCLEASES FOR USE IN THE LIFE SCIENCES, AND IN MEDICAL DIAGNOSTIC, AGRICULTURAL, AND PHARMACEUTICAL RESEARCH;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

Highly specific hammerhead ribozymes are provided that human target estrogen receptor mRNA. These ribozymes, designated RZ1 through RZ7 provide predictable mRNA cleavage products. Methods for inhibiting estrogen-dependent tumor growth, such as that characteristic of breast cancer, are also provided employing these ribozymes. One or both of the ribozymes may be used together or separately with equal efficiency. The ribozymes possess a sequence region with a catalytic core that provides the attributed catalytic activity to these ribozymes.