DEVELOPMENT GENE THERAPY PREPARATIONS

Brand Owner Address Description
THRIVE Apic Bio, Inc. c/o Lab Central 700 Main Street, North Cambridge MA 02139 Development of gene therapy preparations for use in the treatment of autosomal dominant disorders;
 

Where the owner name is not linked, that owner no longer owns the brand

    
Technical Examples
  1. The present invention provides polynucleotides and related polypeptides of the protein ZMNAM isolated from maize endosperm. The invention provides genomic sequence for the ZMNAM gene. ZMNAM is a novel gene and is regulated by gene-specific imprinting. ZMNAM expression is endosperm-specific and expressed throughout the endosperm development, peaking at 25 DAP. Genomic imprinting has been implicated to play a role in endosperm development. Genes regulated by allele-specific imprinting are suspected to be non-essential to seed development. Gene-specific imprinting however, regulates developmentally important genes. The ZMNAM gene, a putative transcriptional factor, may play an important role in endosperm development, which may further affect kernel size, plant vigor during germination and at the early seedling stage.