BACTERIAL STRAIN NUTRITIONAL ADDITIVES

Brand	Owner	Address	Description
BB536	MORINAGA MILK INDUSTRY CO., LTD.	33-1, Shiba 5-chome, Minato-ku, Tokyo Japan	Bacterial strain nutritional additives for use in food as a food supplement and for use in animal feed;
	Where the owner name is not linked, that owner no longer owns the brand

Technical Examples

The present invention relates to a microorganism, preferably a bacterial strain, preferably a non-pathogenic strain, preferably a non-invasive strain, preferably a food grade strain, preferably a gram-positive bacterial strain, delivering a trefoil peptide in vivo. Preferably said trefoil peptide is TFF1. The present invention further relates to a method for the delivery of trefoil peptide to the gastro-intestinal tract comprising the administration of such a bacterial strain. The present invention also relates to a pharmaceutical composition comprising a trefoil peptide delivering bacterium as well as methods of treatment of acute gastro-intestinal inflammatory diseases comprising administration of said transformed bacterial strains, particularly for treating acute colitis, including but not limited to acute flare-ups of Crohn's disease and ulcerative colitis in humans, as well as for treating gastro-intestinal disorders of a similar nature in other animal species.