Derivatives of dillapiol and related monolignans and use thereof

Patent Number: 9386767

Patent Date: 2016-07-12

Patent type: utility

Derivatives of dillapiol, sesamol and related monolignans having the following general formula: These compounds have synergistic properties, inhibit cytochrome P450 enzymes such as human CYP3A4, and can be used as pesticide synergists or pharmaco-enhancers. Accordingly, methods for increasing the efficacy and/or bioavailability of a pharmaceutically active agent and for increasing the potency of a pesticide are described, as are synergistic pesticidal and pharmaceutical compositions.

Inventors

First Name Last Name City State Country
Tony Durst - - -
John T. Arnason - - -
Brian Foster - - -

IPCs

Section Class Sub Class Group Sub Group
A 01 N 43 30
C 07 D 317 54
A 01 N 53 00
C 07 D 317 64
C 07 D 317 68

Assignee

Organization First Name Last Name City State Country
Her Majesty the Queen in right of Canada, as represented by the Minister - - - - -
University of Ottawa - - - - -